Avanafil Impurity 60 CAS CATO-C4X-111860
| CAS No. | CATO-C4X-111860 |
| Molecular Formula | C23H26ClN7O4 |
| Molecular Weight | 499.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Avanafil Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Avanafil Impurity 60 (CAS CATO-C4X-111860) is a certified pharmaceutical impurity reference standard with the molecular formula C23H26ClN7O4 and a molecular weight of 499.95 g/mol.
Avanafil Impurity 60 (C23H26ClN7O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H26ClN7O4 |
| Molecular Weight | 499.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Avanafil Standards
- Avanafil Impurity 120 (CAS CATO-C4X-1118120)
- Avanafil Impurity 122 (CAS CATO-C4X-1118122)
- Avanafil Impurity 147 (CAS CATO-C4X-1118147)
- Avanafil Impurity 29 (CAS CATO-C4X-111829)
- Avanafil Impurity 61 (CAS CATO-C4X-111861)
- Avanafil Impurity 51 (CAS CATO-C4X-111851)
- Avanafil Impurity 48 (CAS 1830294-64-8)
- Avanafil Impurity 154 (CAS CATO-C4X-1118154)
Recommended Standards
- 2-(5-((3-(3-Chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid (CAS 956958-57-9)
- Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, copper complex (CAS 64092-19-9)
- Z-Ala-Pro-Phe-chloromethylketone (CAS 217658-18-9)
- 5-{2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-2H,4H,5H,6H,7H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carbonitrile (CAS 946411-72-9)
- Rosuvastatin Impurity 24 (CAS 894787-93-0)
- Methoxamine Impurity 17 (CAS 776-99-8)
- Prilocaine Impurity 18 (CAS 26073-26-7)
- (S)-4-((tert-Butyldimethylsilyl)oxy)butan-2-ol (CAS 123406-25-7)
- Phthalic acid, bis-4-methylpentyl ester (CAS 259139-51-0)
- 2-((2-Phenylpropyl)amino)propan-1-ol (CAS 1155570-38-9)
- (5-(tert-Butoxy)-2-cyclopropoxyphenyl)(methyl)sulfane (CAS 1243453-72-6)
- 2-(1H-inden-3-yl)acetic acid (CAS 1620-00-4)
- 4-(dimethylamino)-3-fluorobenzene-1-carboximidamide dihydrochloride (CAS 1394042-84-2)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
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