1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one CAS 338979-18-3
| CAS No. | 338979-18-3 |
| Molecular Formula | C23H27ClF3N5O2 |
| Molecular Weight | 497.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one (CAS 338979-18-3), molecular formula C23H27ClF3N5O2 and molecular weight 497.94 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one (C23H27ClF3N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H27ClF3N5O2 |
| Molecular Weight | 497.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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- 2-(4-Methoxyphenyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160264-63-0)
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- 1-(4-Methyl-1,2,5-oxadiazol-3-yl)propan-2-one (CAS 627904-53-4)
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- 5-[3-(trifluoromethyl)phenyl]-1,3-oxazole-4-carboxylic acid (CAS 253315-30-9)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
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