Erlotinib Impurity 34 CAS 183322-17-0
| CAS No. | 183322-17-0 |
| Molecular Formula | C15H23NO6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Erlotinib Impurity 34 (CAS 183322-17-0), a pharmacopoeial impurity reference standard (molecular formula C15H23NO6HCl, MW 349.81 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Erlotinib Impurity 34 (C15H23NO6HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Erlotinib Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H23NO6 HCl |
| Molecular Weight | 349.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Erlotinib Standards
- Erlotinib Impurity 97 (CAS 1012057-39-4)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Hydrochloride Impurity 3 (CAS 1145671-52-8)
- Erlotinib Impurity 51 (CAS 115665-66-2)
- Erlotinib-d6 HCl (CAS 1189953-78-3)
Recommended Standards
- Cefixime Impurity 79 (CAS CATO-C4X-113979)
- Elagolix Impurity 104 (CAS CATO-C4X-2068104)
- Bilastine Impurity 63 (CAS 54176-27-1)
- 7-Bromo-11,11-difluoro-2-methoxy-10,11-dihydrobenzo[6,7]oxepino[3,2-b]pyridine (CAS 2181835-00-5)
- 3,4-dihydro-Pyrido[2,1-c][1,2,4]thiadiazine-9-carboxylic acid-2,2-dioxide (CAS 565165-53-9)
- bis-(2-thienyl) methane (CAS 4341-34-8)
- 2-Oxo-1-(4-phenoxyphenyl)pyrrolidine-3-carboxylic acid (CAS 1017427-68-7)
- Nilotinib Impurity 2 (CAS 943320-48-7)
- Mesatlantin C (CAS 137624-14-7)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com