Erlotinib Impurity 12 CAS 183322-20-5
| CAS No. | 183322-20-5 |
| Molecular Formula | C13H14Cl2N2O3 |
| Molecular Weight | 317.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Erlotinib Impurity 12 (CAS 183322-20-5), a pharmacopoeial impurity reference standard (molecular formula C13H14Cl2N2O3, MW 317.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H14Cl2N2O3, Erlotinib Impurity 12 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 317.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Erlotinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14Cl2N2O3 |
| Molecular Weight | 317.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Erlotinib Standards
- Erlotinib Impurity 11 (CAS 183322-19-2)
- Erlotinib Impurity 54 (CAS CATO-C4X-106954)
- Erlotinib Impurity 80 (CAS 2518426-66-7)
- Erlotinib Impurity 100 (CAS 950596-59-5)
- Erlotinib Impurity 99 (CAS CATO-C4X-106999)
- Erlotinib Impurity 16 (CAS 183322-21-6)
- Erlotinib Impurity 13 (CAS 183322-18-1)
- Erlotinib Impurity 18 (CAS 1683583-37-0)
Recommended Standards
- Lifitegrast Impurity 84 (CAS CATO-C4X-240984)
- N-(4-iodophenyl)-3,3-dimethylbutanamide (CAS 335204-96-1)
- (2E)-1-(4-Bromophenyl)-3-(3-methoxyphenyl)prop-2-en-1-one (CAS 1004554-37-3)
- N-(4-iodophenyl)-2,2-dimethylbutanamide (CAS 335204-97-2)
- Bifendate Impurity 5 (CAS CATO-C4X-25555)
- Alectinib Impurity 2 (CAS 1256579-06-2)
- Celecoxib Impurity 37 (CAS 326-06-7)
- 6-hydroxyimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1781183-23-0)
- 1-(2-Bromo-4-methylphenyl)-ethylamine hydrochloride (CAS 1273596-50-1)
- Dalfampridine D4 (CAS 26257-21-6)
- 5-hexenoic acid (CAS 1577-22-6)
- 3-Bromo-4-methylthiophene (CAS 30318-99-1)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-methoxy-5-(trifluoromethoxy)pyridine (CAS 1805111-71-0)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com