Erlotinib Impurity 100 CAS 950596-59-5
| CAS No. | 950596-59-5 |
| Molecular Formula | C16H23N3O4 |
| Molecular Weight | 321.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Erlotinib Impurity 100 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Erlotinib Impurity 100 (CAS 950596-59-5), a pharmacopoeial impurity reference standard (molecular formula C16H23N3O4, MW 321.37 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Erlotinib Impurity 100 (C16H23N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H23N3O4 |
| Molecular Weight | 321.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 99 (CAS CATO-C4X-106999)
- Erlotinib Impurity 16 (CAS 183322-21-6)
- Erlotinib Impurity 18 (CAS 1683583-37-0)
- Erlotinib Impurity 106 (CAS 1239843-56-1)
- Erlotinib Impurity 135 (CAS CATO-C4X-1069135)
- Erlotinib Impurity 11 (CAS 183322-19-2)
- Erlotinib Impurity 12 (CAS 183322-20-5)
- Erlotinib impurity 132 (CAS CATO-C4X-1069132)
Recommended Standards
- tert-butyl (Z)-(1-(((amino(phenyl)methylene)amino)oxy)-2-methyl-1-oxopropan-2-yl)carbamate (CAS CATO-C3D-263031)
- Tert-butyl methyl(1-(4-nitrophenyl)pyrrolidin-3-yl)carbamate (CAS 863401-75-6)
- Ivabradine Impurity 35 (CAS CATO-C4X-111935)
- tert-Butyl 4-[3-(methoxycarbonyl)pyridin-2-yl]piperazine-1-carboxylate (CAS 2055119-02-1)
- New Drug Impurity 63 D5 (CAS CATO-C3D-262963)
- Phloroglucinol impurity 59 (CAS 1521-62-6)
- Dapagliflozin Impurity 86 (CAS 1528636-07-8)
- Ethyl 1-(difluoromethyl)-3-iodo-1H-pyrazole-4-carboxylate (CAS 2221016-71-1)
- [1,3]Dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine (CAS 522-30-5)
- Ethyl 3-(2-chloro-4-nitrophenylamino)-2-cyanoacrylate (CAS 954118-32-2)
- (3R)-3-(4-Fluoro-2-methylphenyl)piperazin-2-one (CAS 1153574-57-2)
- 2-Ethyl-3,5-diiodopyridin-4-amine (CAS 1352393-71-5)
- Pitavastatin Impurity 92 (CAS 1159588-21-2)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com