Alectinib Impurity 2 CAS 1256579-06-2
| CAS No. | 1256579-06-2 |
| Molecular Formula | C19H13BrN2O2 |
| Molecular Weight | 381.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Alectinib Impurity 2.
As a process- or degradation-related impurity, Alectinib Impurity 2 (CAS 1256579-06-2, C19H13BrN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Alectinib Impurity 2 (C19H13BrN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Alectinib Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H13BrN2O2 |
| Molecular Weight | 381.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Alectinib Standards
- Alectinib Impurity 66 (CAS CATO-C4X-283666)
- Alectinib Impurity 54 (CAS CATO-C4X-283654)
- Alectinib Impurity 53 (CAS CATO-C4X-283653)
- Alectinib impurity 28 (CAS 2412921-44-7)
- Alectinib Impurity 75 (CAS CATO-C4X-283675)
- Alectinib Impurity 40 (CAS CATO-C4X-283640)
- Alectinib impurity 21 (CAS 1256584-91-4)
- Alectinib Impurity 55 (CAS CATO-C4X-283655)
Recommended Standards
- Tenofovir Disoproxil Impurity 61 (CAS CATO-C4X-107661)
- Imidacloprid Impurity 1 (CAS 105828-41-9)
- N-(4-bromo-2-picolinoylphenyl)benzamide (CAS 22753-88-4)
- 1-(3-Bromo-2,5,6-trifluoro-4-methoxyphenyl)-4-propylcyclohexanol (CAS 1262220-70-1)
- Eugenol Impurity 10 (CAS CATO-C4X-198910)
- Lenacapavir impurity 18 (CAS 1417983-10-8)
- Moxifloxacin Impurity 16 (CAS 28749-88-4)
- Ac-Ser4-Cetrorelix X TFA Salt (CAS CATO-C4X-201414)
- 2-(2-Amino-4-methylpentanamido)-4-methylpentanoic acid (CAS 2883-36-5)
- Methyl 4-(1,1-difluoroethyl)-2-nitrobenzoate (CAS 912575-27-0)
- 7-Chloro-2-cyclobutyl-3H-imidazo[4,5-b]pyridine (CAS 1125745-05-2)
- (E)-3-((1-Methyl-1H-Indol-3-Yl)Methylene)-1H-Pyrrolo[3,2-B]Pyridin-2(3H)-One (CAS 1243657-78-4)
- tert-Butyl 9-oxo-2,8-diazaspiro[5.5]undecane-2-carboxylate (CAS 2414377-55-0)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com