Dabigatran Impurity 86 CAS 18358-63-9
| CAS No. | 18358-63-9 |
| Molecular Formula | C9H11NO2 |
| Molecular Weight | 165.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dabigatran Impurity 86.
Dabigatran Impurity 86 (CAS 18358-63-9) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11NO2 and a molecular weight of 165.19 g/mol.
Structurally, Dabigatran Impurity 86 (C9H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 165.19 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dabigatran Impurity 86 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11NO2 |
| Molecular Weight | 165.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Dabigatran Standards
- Dabigatran Impurity 34 (CAS 58906-62-0)
- Dabigatran Impurity 35 (CAS 265659-62-9)
- Dabigatran Impurity 36 (CAS 265659-61-8)
- Dabigatran Impurity 94 (CAS 58906-64-2)
- Dabigatran Impurity 85 (CAS 104961-64-0)
- Dabigatran Impurity 42 (CAS 42288-26-6)
- Dabigatran Impurity 96 (CAS 16156-50-6)
- Dabigatran Etexilate Impurity 84 (CAS 175867-55-7)
Recommended Standards
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- Fluticasone Furoate Impurity 8 (CAS CATO-C4X-32548)
- Dotinurad Impurity 24 (CAS 4433-53-8)
- Lifitegrast Impurity 16 (CAS 2322380-18-5)
- (3-Chloropyridin-4-yl)methanamine hydrochloride (CAS 2101504-69-0)
- n-Methyl-1-(pyridazin-3-yl)piperidin-3-amine (CAS 1247087-42-8)
- LTI-291 (CAS 1919820-28-2)
- 2-(2,5-Dioxo-3-pyrrolidinyl)acetic Acid (CAS 84767-78-2)
- 5-[(4-bromo-1H-pyrazol-1-yl)methyl]furan-3-carboxylic acid (CAS 1247390-92-6)
- 2-Aminopyridine 1-oxide hydrochloride (CAS 57097-28-6)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
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