Dabigatran Impurity 42 CAS 42288-26-6
| CAS No. | 42288-26-6 |
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 176.17 g/mol gives Dabigatran Impurity 42 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dabigatran Impurity 42 (CAS 42288-26-6, C9H8N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dabigatran Impurity 42 (C9H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dabigatran Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 2 |
Related Dabigatran Standards
- Dabigatran Impurity 96 (CAS 16156-50-6)
- Dabigatran Impurity 85 (CAS 104961-64-0)
- Dabigatran Impurity 86 (CAS 18358-63-9)
- Dabigatran Impurity 34 (CAS 58906-62-0)
- Dabigatran Impurity 35 (CAS 265659-62-9)
- Dabigatran Impurity 36 (CAS 265659-61-8)
- Dabigatran Impurity 94 (CAS 58906-64-2)
- Dabigatran Etexilate Impurity 84 (CAS 175867-55-7)
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- 1-ethyl-4-formyl-pyrrole-2-carboxylic acid (CAS 1642797-72-5)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
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