N-(3-Chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine CAS 184356-50-1
| CAS No. | 184356-50-1 |
| Molecular Formula | C14H8ClFN4O2 |
| Molecular Weight | 318.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-Chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine (CAS 184356-50-1), molecular formula C14H8ClFN4O2 and molecular weight 318.69 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(3-Chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(3-Chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClFN4O2 |
| Molecular Weight | 318.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(3-Chloro-2-fluorophenyl)-6-nitroquinazolin-4-amine (CAS 1290545-22-0)
- 5-Chloro-8-(4-fluoro-2-nitrophenoxy)quinoline (CAS 400078-01-5)
- 2-(2-Chloro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester (CAS 1033586-26-3)
- Benzyl (6-chloro-8-oxo-7H-purin-9(8H)-yl)carbamate (CAS 15206-32-3)
- 1-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methyl-1H-imidazol-4-yl}-1-ethanone oxime (CAS 251096-48-7)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(furan-2-ylmethyl)acetamide (CAS 691870-10-7)
- 5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2381044-50-2)
- 6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (CAS 318959-11-4)
Recommended Standards
- (2R,3R,4S,5R)-5-(2-Chloro-6-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 758705-70-3)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carboxylate (CAS 321430-87-9)
- 6-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2869830-81-7)
- Ataluren Impurity 1 (CAS CATO-C4X-30061)
- [4-(Cyanomethyl)-3-methoxyphenyl]boronic acid (CAS 2377608-80-3)
- 2-Chloro-N-(5-methoxypyrimidin-2-yl)acetamide (CAS 374684-44-3)
- 2-(4-(Tert-butyl)phenoxy)acetamide (CAS 28329-43-3)
- tert-Butyl 4-p-tolylpyrrolidin-3-ylcarbamate (CAS 1022605-11-3)
- Tert-butyl (1-(3,3-dimethylbutanoyl)piperidin-4-yl)carbamate (CAS 1286272-99-8)
- 2-(4-(Difluoromethyl)-6-iodo-3-methylpyridin-2-yl)acetonitrile (CAS 1805543-56-9)
- (4-([1,1'-Biphenyl]-4-yl)-1H-imidazol-2-yl)methanamine (CAS 335246-58-7)
- 3-Bromo Lidocaine (CAS 1044658-01-6)
- 5-Methoxy-1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1262294-19-8)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
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