Temozolomide Impurity 20 CAS 18514-52-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.18514-52-8
Molecular FormulaC4H4N4
Molecular Weight108.10 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Temozolomide Impurity 20 CAS 18514-52-8 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Temozolomide Impurity 20 (CAS 18514-52-8) is a certified pharmaceutical impurity reference standard with the molecular formula C4H4N4 and a molecular weight of 108.10 g/mol.

Temozolomide Impurity 20 (C4H4N4) contains a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H4N4
Molecular Weight108.10 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1962
Nitrogen Atoms4

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