(2-Chloro-4-ethynylphenyl)methanamine CAS 1852161-01-3
| CAS No. | 1852161-01-3 |
| Molecular Formula | C9H8ClN |
| Molecular Weight | 165.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 165.62 g/mol gives (2-Chloro-4-ethynylphenyl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (2-Chloro-4-ethynylphenyl)methanamine (CAS 1852161-01-3), a certified reference material (molecular formula C9H8ClN, MW 165.62 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, (2-Chloro-4-ethynylphenyl)methanamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClN |
| Molecular Weight | 165.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(2-Chloro-4-methylphenyl)acetonitrile (CAS 1000554-63-1)
- 4-Chloro-3,5-dimethylbenzonitrile (CAS 1097629-24-7)
- 5-Chloro-1-methyl-1H-indole (CAS 112398-75-1)
- 2-chloro-5-methoxy-pyridin-4-ol (CAS 1196145-74-0)
- 2-Chloro-N-(3-hydroxypropyl)propanamide (CAS 1211481-04-7)
- 2-Chloro-4,5-dimethylbenzonitrile (CAS 1242339-03-2)
- 3-Chloro-1-methyl-1H-indole (CAS 124589-41-9)
- 5-Chloro-2-methoxypyridin-3-ol (CAS 1261365-86-9)
Recommended Standards
- (2-Chloro-5-ethynylphenyl)methanamine (CAS 1849194-31-5)
- 5-(chloromethyl)-2-methylbenzonitrile (CAS 188984-17-0)
- 2-Chloro-3-phenylpropanenitrile (CAS 17849-62-6)
- 3-(Chloromethyl)-5-methylbenzonitrile (CAS 188984-18-1)
- 2-Amino-5-(3-((4-(2-(chloromethyl)-1,3-dioxolan-2-yl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-52-7)
- Methyl (2S,4S)-4-(2-ethylphenoxy)-2-pyrrolidinecarboxylate (CAS 1217857-92-5)
- 2-{[(2-methylphenyl)(phenyl)methoxy]methyl}oxirane (CAS 19574-83-5)
- 2-Chloro-5-iodobenzotrifluoride (CAS 260355-20-2)
- {4-[2-(dimethylamino)ethyl]phenyl}boronic acid (CAS 950739-39-6)
- 1,1-Dimethylethyl N-[2-nitro-4-(trifluoromethyl)phenyl]carbamate (CAS 579474-18-3)
- (4-Amino-5-bromo-2-chlorophenyl)methanol (CAS 1807757-01-2)
- 1-(5-bromo-2-methoxyphenyl)pyrrolidine (CAS 1541478-33-4)
- N-(3,5-Dichlorophenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 577963-76-9)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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