2-Chloro-6-fluoro-4-methylquinoline CAS 18529-12-9
| CAS No. | 18529-12-9 |
| Molecular Formula | C10H7ClFN |
| Molecular Weight | 195.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-6-fluoro-4-methylquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Chloro-6-fluoro-4-methylquinoline (CAS 18529-12-9), a certified reference material (molecular formula C10H7ClFN, MW 195.62 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-6-fluoro-4-methylquinoline (C10H7ClFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClFN |
| Molecular Weight | 195.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5-fluoro-8-methylquinoline (CAS 1065093-43-7)
- 4-Chloro-6-fluoro-8-methylquinoline (CAS 1065093-47-1)
- 4-Chloro-7-fluoro-8-methylquinoline (CAS 1065093-51-7)
- 2-Chloro-8-fluoro-4-methylquinoline (CAS 1171919-59-7)
- 1-(3-Chloro-4-fluorophenyl)cyclopropanecarbonitrile (CAS 1205640-59-0)
- 1-Chloro-7-fluoro-3-methylisoquinoline (CAS 1206982-03-7)
- 1-(2-Chloro-6-fluorophenyl)cyclopropanecarbonitrile (CAS 124276-45-5)
- 1-(2-Chloro-4-fluorophenyl)cyclopropanecarbonitrile (CAS 1260650-46-1)
Recommended Standards
- 4-chloro-6-fluoro-2-methylquinoline (CAS 18529-01-6)
- 2-(4-Chloro-3-fluorophenyl)pyrrole (CAS 1936405-09-2)
- 4-Chloro-5-fluoro-2-methylquinoline (CAS 1799421-05-8)
- 1-(3-Chloro-4-fluorophenyl)-1H-pyrrole (CAS 383137-55-1)
- Dabsyl-L-tryptophan (CAS 97685-00-2)
- {4-[(methylsulfanyl)methyl]phenyl}methanamine (CAS 854304-48-6)
- 1-(7-(2-Fluorophenyl)-1,4-thiazepan-4-yl)-3-(furan-2-yl)prop-2-en-1-one (CAS 1706508-00-0)
- 7-METHOXY-2,3,4,5-TETRAHYDRO-1H-BENZO[C]AZEPINE HCL (CAS 57644-67-4)
- (R)-2-(2-bromo-3-methylphenyl)pyrrolidine (CAS 1213035-92-7)
- Manassantin B (CAS 88497-88-5)
- 1220020-06-3 N-(3-Methylphenyl)-3-piperidinecarboxamidehydrochloride (CAS 1220020-06-3)
- 2-(5-Methylpyridin-2-yl)propan-2-ol (CAS 40472-51-3)
- 1H-Indene-1-carboxylic acid (CAS 5020-21-3)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com