4-(2-Chloroacetyl)-1,3-dimethyl-1H-pyrazol-5(4H)-one CAS 185746-06-9
| CAS No. | 185746-06-9 |
| Molecular Formula | C7H9ClN2O2 |
| Molecular Weight | 188.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2-Chloroacetyl)-1,3-dimethyl-1H-pyrazol-5(4H)-one (CAS 185746-06-9), molecular formula C7H9ClN2O2 and molecular weight 188.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-(2-Chloroacetyl)-1,3-dimethyl-1H-pyrazol-5(4H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 188.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2-Chloroacetyl)-1,3-dimethyl-1H-pyrazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9ClN2O2 |
| Molecular Weight | 188.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroacetyl Standards
- 5-(2-chloroacetyl)furan-3-carboxylic acid (CAS 1251924-13-6)
- 1-(2-Chloroacetyl)pyrimidine-2,4(1H,3H)-dione (CAS 89581-68-0)
- 4-(2-Chloroacetyl)-5,5-dimethyl-4,5-dihydro-3H-1,2,4-triazol-3-one (CAS 130138-03-3)
- N-(Chloroacetyl)-3-fluoroaniline (CAS 350-81-2)
- 5-(2-Chloroacetyl)furan-3-carboxamide (CAS 1251923-22-4)
- n-(2-Chloroacetyl)furan-2-carboxamide (CAS 878466-49-0)
- 1-(2-Chloroacetyl)piperidine-4-carbonitrile (CAS 1003320-12-4)
- N-(2-chloroacetyl)-1H-pyrrole-2-carboxamide (CAS 1000931-83-8)
Recommended Standards
- Methyl 4-chloro-1-ethyl-1H-pyrazole-3-carboxylate (CAS 1856075-60-9)
- 2-(4-Chlorobenzylidene)malononitrile (CAS 1867-38-5)
- 5-Chloro-6-hydroxy-2-propylpyrimidin-4(3H)-one (CAS 1850-96-0)
- 3-Chloro-4-propyl-1H-pyrazole-5-carboxylic acid (CAS 1922699-52-2)
- 2-(2-(3-(4-Methoxyphenyl)propanamido)thiazol-4-yl)acetic acid (CAS 931374-27-5)
- 5-Chloro-2,3-dihydrobenzofuran-7-carbaldehyde (CAS 82060-93-3)
- Ethyl 2-(2-fluoroethoxy)acetate (CAS 372-51-0)
- 3-Cyclopropoxy-N-methyl-5-(methylthio)picolinamide (CAS 1243363-38-3)
- N-(4-Ethoxy-6-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-2-yl)acetamide (CAS 917760-02-2)
- Dibutyldecylphosphonate (CAS 36378-71-9)
- (2S,3R,4R)-3-Amino-4-(hydroxymethyl)-2-methylpyrrolidine-1-carbaldehyde (CAS 220280-45-5)
- Azelastine Impurity 11 3HCl (CAS 169123-29-9)
- 3-((4-Chlorophenyl)thio)-11-methyl-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one (CAS 97416-80-3)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com