8-Methyl-2-(trifluoromethyl)quinoline CAS 1860-46-4
| CAS No. | 1860-46-4 |
| Molecular Formula | C11H8F3N |
| Molecular Weight | 211.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-Methyl-2-(trifluoromethyl)quinoline (CAS 1860-46-4), a certified reference material (molecular formula C11H8F3N, MW 211.18 g/mol) for analytical method development and quality control.
Structurally, 8-Methyl-2-(trifluoromethyl)quinoline (C11H8F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 211.18 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 8-Methyl-2-(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F3N |
| Molecular Weight | 211.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-[6-(trifluoromethyl)pyridin-2-yl]acetic acid (CAS 1000565-32-1)
- 2-[4-(Trifluoromethyl)phenyl]pyrrole (CAS 115464-88-5)
- 2-[2-(Trifluoromethyl)phenyl]pyrrole (CAS 116332-50-4)
- Ethyl 3-(trifluoromethyl)pyrrolidine-3-carboxylate (CAS 1211537-93-7)
- 5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester (CAS 124236-37-9)
- 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS 124276-61-5)
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- 1-[3-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS 124305-68-6)
Recommended Standards
- 2-(2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethylidene)hydrazinecarboxamide (CAS 18149-58-1)
- 6-Methyl-2-(trifluoromethyl)quinoline (CAS 1860-47-5)
- 7-Methyl-2-(trifluoromethyl)quinoline (CAS 176722-74-0)
- 3-Methyl-6-(trifluoromethyl)isoquinoline (CAS 1880496-99-0)
- 1-Pyridin-2-ylpiperidine-4-carboxylic acid;hydrochloride (CAS 1357353-07-1)
- 3-Chloro-2-fluoropyridin-4-amine (CAS 1227577-11-8)
- Methyl 2-(4-((2-chlorothiazol-5-yl)methoxy)phenyl)acetate (CAS 478064-76-5)
- 4-(2-(4-Methylfuran-3-yl)vinyl)furan-3-carbaldehyde (CAS 64862-05-1)
- Methyl 2-(methylamino)-1,3-thiazole-5-carboxylate (CAS 1384661-33-9)
- 2-[(1-Boc-4-piperidyl)oxy]ethanamine (CAS 442126-36-5)
- 2-((3-Oxo-2,3-dihydro-1,2,4-triazin-5-yl)amino)acetic acid (CAS 221663-54-3)
- [(3-isopropoxy-2-thienyl)methyl]amine (CAS 1428234-18-7)
- 6-((Tetrahydro-2H-pyran-4-yl)oxy)nicotinamide (CAS 1334490-82-2)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
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