Ruxolitinib Impurity 13 CAS 1865785-69-8
| CAS No. | 1865785-69-8 |
| Molecular Formula | C7H12N2O2 |
| Molecular Weight | 156.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ruxolitinib Impurity 13 (C7H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Ruxolitinib Impurity 13 (CAS 1865785-69-8), a pharmacopoeial impurity reference standard (molecular formula C7H12N2O2, MW 156.18 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ruxolitinib Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12N2O2 |
| Molecular Weight | 156.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Related Ruxolitinib Standards
- Ruxolitinib impurity 227 (CAS 350483-64-6)
- Ruxolitinib Impurity 60 (CAS CATO-C4X-205860)
- Ruxolitinib Impurity 59 (CAS 2802349-76-2)
- Ruxolitinib impurity 48 (CAS CATO-C4X-205848)
- Ruxolitinib Impurity 232 (CAS CATO-C4X-2058232)
- Ruxolitinib Impurity 109 (CAS CATO-C4X-2058109)
- Ruxolitinib Impurity 87 (CAS CATO-C4X-205887)
- Ruxolitinib Impurity 125 (CAS CATO-C4X-2058125)
Recommended Standards
- Brivaracetam impurity 85 (CAS CATO-C4X-200785)
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- Carbidopa Impurity 27 (CAS CATO-C4X-231027)
- Rivaroxaban Impurity 62 (CAS 89283-13-6)
- Uridine Impurity 21 (CAS CATO-C4X-233421)
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- N-(Cyclobutylmethyl)benzamide (CAS 861786-97-2)
- 110207-62-0 Acetyl-Cholecystokinin Octapeptide (2-8) (sulfated) MFCD00133565 (CAS 110207-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com