Ruxolitinib Impurity 59 CAS 2802349-76-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2802349-76-2
Molecular FormulaC8H15N3
Molecular Weight153.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ruxolitinib Impurity 59 CAS 2802349-76-2 chemical structure

Description

The molecular framework of Ruxolitinib Impurity 59 (C8H15N3) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Ruxolitinib Impurity 59 (CAS 2802349-76-2) is a certified pharmaceutical impurity reference standard with the molecular formula C8H15N3 and a molecular weight of 153.22 g/mol.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Ruxolitinib Impurity 59 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H15N3
Molecular Weight153.22 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2003
Nitrogen Atoms3

Related Ruxolitinib Standards

Recommended Standards

Why CATO?