| CAS No. | 18686-82-3 |
| Molecular Formula | C2H2N2S2 |
| Molecular Weight | 118.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Cefazolin Impurity 46 (CAS 18686-82-3) is a certified pharmaceutical impurity reference standard with the molecular formula C2H2N2S2 and a molecular weight of 118.18 g/mol.
Owing to a nitrile group, sulfur-containing functionality, Cefazolin Impurity 46 is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 118.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefazolin Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C2H2N2S2 |
| Molecular Weight | 118.18 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |