Ceftizoxime impurity 97 CAS 186957-49-3
| CAS No. | 186957-49-3 |
| Molecular Formula | C26H26N10O10S4 |
| Molecular Weight | 766.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ceftizoxime impurity 97 (CAS 186957-49-3, C26H26N10O10S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ceftizoxime impurity 97 (C26H26N10O10S4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 766.81 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26N10O10S4 |
| Molecular Weight | 766.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 4 |
Related Ceftizoxime Standards
- Ceftizoxime Impurity 36 (CAS CATO-C4X-179336)
- Ceftizoxime Impurity 84 (CAS CATO-C4X-179384)
- Ceftizoxime Open-ring Dimer Impurity 55 (CAS CATO-C4X-179355)
- Ceftizoxime Dimer Impurity 38 (CAS CATO-C4X-179338)
- Ceftizoxime Open-ring decarboxylation Dimer Impurity 57 (CAS CATO-C4X-179357)
- Ceftizoxime Impurity 91 (CAS CATO-C4X-179391)
- Ceftizoxime Open-ring decarboxylation Dimer Impurity 56 (CAS CATO-C4X-179356)
- Ceftizoxime Alapivoxil (CAS 135821-54-4)
Recommended Standards
- Rifampicin Impurity 14 (CAS CATO-C4X-145614)
- (E,E)-Ceftizoxime Impurity 67 (CAS CATO-C4X-179367)
- 7,10-Bis(4-(diphenylamino)phenyl)dibenzo[f,h]quinoxaline-2,3-dicarbonitrile (CAS 1803287-94-6)
- Grazoprevir (CAS 1350514-68-9)
- Azelastine EP Impurity E (Z-Isomer) (CAS 105279-16-1)
- Indobufen Impurity N5 (CAS 15494-55-0)
- Tolvaptan Impurity 16 (CAS 160129-45-3)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
- 4-(2-(Benzyl(methyl)amino)-1-hydroxyethyl)-1,2-phenylene bis(2,2-dimethylpropanoate) (CAS 133789-72-7)
- 4-Phenyl-4-sulfanyl-2-(trifluoromethyl)butanoic acid (CAS 870703-90-5)
- 4-Bromo-2-(difluoromethyl)-6-(trifluoromethyl)pyridin-3-ol (CAS 1805170-55-1)
- 1-benzyl-5-methylpyrrolidin-2-one (CAS 91640-09-4)
- (E)-N-(2-methyl-4-(o-tolyldiazenyl)phenyl)acetamide (CAS 588-23-8)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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