Tolvaptan Impurity 16 CAS 160129-45-3
| CAS No. | 160129-45-3 |
| Molecular Formula | C10H10ClNO |
| Molecular Weight | 195.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 195.65 g/mol gives Tolvaptan Impurity 16 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tolvaptan Impurity 16 (CAS 160129-45-3) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10ClNO and a molecular weight of 195.65 g/mol.
Tolvaptan Impurity 16 (C10H10ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO |
| Molecular Weight | 195.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tolvaptan Standards
- Tolvaptan Impurity 49 (CAS 116815-03-3)
- Tolvaptan Impurity N1 (CAS 247237-56-5)
- Tolvaptan Impurity 33 (CAS 1310357-40-4)
- Tolvaptan Impurity N2 (CAS 30459-70-2)
- Tolvaptan Impurity 17 (CAS 1975-51-5)
- Tolvaptan Impurity 73 (CAS 1316312-24-9)
- Tolvaptan Impurity 78 (CAS 1863916-82-8)
- Tolvaptan Impurity 74 (CAS CATO-C4X-195574)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com