Aspirin Impurity 8 CAS 18698-59-4

Description

Compared with other compounds in its class, the molecular weight of 222.19 g/mol gives Aspirin Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Aspirin Impurity 8 (CAS 18698-59-4), a pharmacopoeial impurity reference standard (molecular formula C11H10O5, MW 222.19 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Aspirin Impurity 8 (C11H10O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Aspirin Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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