Lidocaine EP Impurity A HCl CAS 21436-98-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.21436-98-6
Molecular FormulaC8H11N
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lidocaine EP Impurity A HCl CAS 21436-98-6 chemical structure

Description

CATO supplies Lidocaine EP Impurity A HCl (CAS 21436-98-6), a pharmacopoeial impurity reference standard (molecular formula C8H11NHCl, MW 157.64 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C8H11NHCl, Lidocaine EP Impurity A HCl contains a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 157.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H11N HCl
Molecular Weight157.64 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1963
Halogen ContentCl-containing
Nitrogen Atoms1

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