Diclofenac potassium CAS 15307-81-0
| CAS No. | 15307-81-0 |
| Molecular Formula | C14H10Cl2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diclofenac potassium (CAS 15307-81-0), molecular formula C14H10Cl2NO2K and molecular weight 334.24 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Diclofenac potassium (C14H10Cl2NO2K) contains a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 334.24 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Diclofenac potassium meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10Cl2NO2 K |
| Molecular Weight | 334.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 21 (CAS 105836-68-8)
- Diclofenac Impurity 8 (CAS 106610-60-0)
- Diclofenac Epolamine (CAS 119623-66-4)
- Diclofenac Impurity 60 (CAS 120339-20-0)
- Diclofenac Impurity 19 (CAS 1205-40-9)
- Diclofenac Impurity 31 (CAS 1219112-85-2)
- Diclofenac Sodium Impurity 34 (CAS 123790-84-1)
- Diclofenac impurity f (CAS 124426-56-8)
Recommended Standards
- Heptyl (R)-4-(1-amino-2,2,2-trifluoroethyl)benzoate (CAS 1213068-04-2)
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- 5-Amino-4-(benzo[d]thiazol-2-yl)-1-(4-methoxyphenyl)-1,2-dihydro-3h-pyrrol-3-one (CAS 325832-84-6)
- (E)-Ethyl 3-(4-Cyanophenyl)Acrylate (CAS 62174-99-6)
- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (CAS 159276-63-8)
- 4-Bromo-2,6-diethylbenzonitrile (CAS 1200131-07-2)
- Loratadine EP Impurity C (CAS 165739-83-3)
- 3-((5-Bromo-2-ethoxy-4-formylphenoxy)methyl)benzoic acid (CAS 1159693-38-5)
- n-[3-(piperidin-1-yl)propyl]piperidine-4-carboxamide dihydrochloride (CAS 1172430-39-5)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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