N-Benzyl-3-fluoro-5-hydroxybenzamide CAS 1881292-72-3
| CAS No. | 1881292-72-3 |
| Molecular Formula | C14H12FNO2 |
| Molecular Weight | 245.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-Benzyl-3-fluoro-5-hydroxybenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-Benzyl-3-fluoro-5-hydroxybenzamide (CAS 1881292-72-3) is a high-purity analytical reference standard with the molecular formula C14H12FNO2 and a molecular weight of 245.25 g/mol.
The molecular framework of N-Benzyl-3-fluoro-5-hydroxybenzamide (C14H12FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12FNO2 |
| Molecular Weight | 245.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(tert-Butoxycarbonyl)-4-fluoro-2-azabicyclo[2.1.1]hexane-1-carboxylic acid (CAS 1824278-88-7)
- N-Benzyl-2-fluoro-5-hydroxybenzamide (CAS 1881322-17-3)
- 2-(Benzyloxy)-5-fluorobenzamide (CAS 1823241-87-7)
- 2-[(3Z)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-ylidene]-2-fluoroacetic acid (CAS 1937358-25-2)
- (2E)-1-(2,5-Dichlorophenyl)-3-(3-methylthiophen-2-yl)prop-2-en-1-one (CAS 1354942-04-3)
- 2-Bromo-1-(4-(phenylthio)phenyl)ethanone 28179-34-2 (CAS 28179-34-2)
- 5-[(diethylamino)methyl]quinolin-8-ol (CAS 22506-13-4)
- 5-Hydroxy Propafenone-d5 Hydrochloride (CAS 1215370-87-8)
- ethyl 4-chloro-2-(methylsulphinyl)-8-(trifluoromethyl)quinoline-3-carboxylate (CAS 662138-37-6)
- Loxoprofen Impurity 59 (CAS 132560-67-9)
- 4-tert-Butyl-N'-[(1E)-{4-[(3-chlorophenyl)methoxy]phenyl}methylidene]benzohydrazide (CAS 477863-17-5)
- 2-[(E)-2-(2,4-Dichlorophenyl)ethenyl]-1H-imidazole (CAS 213179-56-7)
- Prednisone Impurity 5 (CAS 215095-77-5)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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