Salbutamol Impurity 69 CAS 18866-78-9
| CAS No. | 18866-78-9 |
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 225.28 g/mol gives Salbutamol Impurity 69 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Salbutamol Impurity 69 (CAS 18866-78-9) is a certified pharmaceutical impurity reference standard with the molecular formula C12H19NO3 and a molecular weight of 225.28 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Salbutamol Impurity 69 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 225.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Salbutamol Impurity 69 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 68 (CAS 18910-63-9)
- Salbutamol Impurity 71 (CAS 232590-81-7)
- Salbutamol Impurity 196 (CAS CATO-C4X-1176196)
- Salbutamol EP Impurity C (CAS 18910-68-4)
- Salbutamol Impurity 84 (CAS CATO-C4X-117684)
- Salbutamol Impurity 55 (CAS 115787-52-5)
- Salbutamol Impurity 92 (CAS CATO-C4X-117692)
- Salbutamol Impurity 67 (CAS CATO-C4X-117667)
Recommended Standards
- Vildagliptin Impurity 7 (CAS 1032564-18-3)
- Terbutaline impurity 116 (CAS CATO-C4X-1183116)
- Memantine impurity 55 (CAS CATO-C4X-105855)
- Terbutaline Impurity 24 (CAS CATO-C4X-118324)
- Edoxaban Impurity 13 (CAS 767625-11-6)
- Metaraminol Impurity 25 (CAS CATO-C4X-225225)
- Lenvatinib Impurity 70 (CAS 619-16-9)
- Methyl 4-(difluoromethoxy)-3-nitrobenzoate (CAS 1154278-25-7)
- 7-amino-1,5-naphthyridine-3-carboxylic acid (CAS 2089649-99-8)
- 7-bromo-5-chloro-1H-indazole (CAS 875305-86-5)
- cis-3-Fluorocyclobutanamine hydrochloride (CAS 1408075-13-7)
- 2-(4-Bromobenzyl)-4,4-dimethyl-4,5-dihydrooxazole (CAS 176324-85-9)
- 3-Chloro-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87779-03-1)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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