7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one CAS 188967-75-1
| CAS No. | 188967-75-1 |
| Molecular Formula | C15H8ClF2NO2 |
| Molecular Weight | 307.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one (CAS 188967-75-1), molecular formula C15H8ClF2NO2 and molecular weight 307.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 307.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H8ClF2NO2 |
| Molecular Weight | 307.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-(2-chloro-4-fluorosulphonylanilino)-4-oxobut-2-enoic acid (CAS 680213-38-1)
- 6-Chloro-1-(3,5-difluorophenyl)-1H-indole-3-carboxylic acid (CAS 921195-18-8)
- Phenyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 72850-69-2)
- N-(5-chloro-2-hydroxy-4-nitrophenyl)-N'-phenylurea (CAS 117745-34-3)
- 5-Chloro-2-methoxy-3-nitrophenyl benzoate (CAS 1221792-84-2)
- 3-(2-Chloro-5-methoxyphenyl)-5-nitrobenzoic acid (CAS 1261892-79-8)
- 5-Chloro-3-((5-methoxy-4-oxo-4H-pyran-2-yl)methyl)benzo[d]oxazol-2(3H)-one (CAS 1432086-02-6)
- 2-(5-Chloro-2-oxobenzo[d]oxazol-3(2H)-yl)-N-(5-methylisoxazol-3-yl)acetamide (CAS 902254-96-0)
Recommended Standards
- 2-(4-Chlorophenyl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 187998-87-4)
- Norflurazon-13C,d3 (CAS 1346603-47-1)
- Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 685108-15-0)
- 7-(Difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride (CAS 861412-81-9)
- 2-((Thiophen-3-ylmethyl)amino)acetic acid (CAS 933702-35-3)
- 4-(2-Fluoroethoxy)benzoyl chloride (CAS 145304-36-5)
- Ethyl 2-bromo-6-cyano-4-(trifluoromethyl)benzoate (CAS 1805186-77-9)
- (9H-Fluoren-2-yl)methanamine (CAS 34577-93-0)
- 2-(2-Oxopentyl)-1,3-oxathiolan-4-yl acetate (CAS 143446-73-5)
- 1-(3-(2-Aminoethyl)-5'-(2,5-difluorophenyl)-6,7-difluoro-3'H-spiro[chromane-4,2'-[1,3,4]thiadiazol]-3'-yl)ethan-1-one (CAS 1146209-50-8)
- 2-(Benzylthio)-4-(pyrrolidin-1-yl)thieno[3,2-d]pyrimidine (CAS 339018-94-9)
- 2-Bromo-4-(trifluoromethyl)benzo[d]thiazole (CAS 898748-19-1)
- (R)-2-((tert-Butoxycarbonyl)amino)-3,3-difluoropropanoic acid (CAS 2349311-08-4)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com