Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate CAS 685108-15-0
| CAS No. | 685108-15-0 |
| Molecular Formula | C11H9ClF3N3O2 |
| Molecular Weight | 307.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 685108-15-0), molecular formula C11H9ClF3N3O2 and molecular weight 307.66 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 307.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9ClF3N3O2 |
| Molecular Weight | 307.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one (CAS 338420-89-6)
- 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one (CAS 97986-18-0)
- 3-{[(4-chloro-6-methylpyrimidin-2-yl)amino]methylene}-1,1,1-trifluoropentane-2,4-dione (CAS 649665-78-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860650-63-1)
- 8-Chloro-1,3-dinitro-10H-phenoxazine (CAS 105261-75-4)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1799-70-8)
- 7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one (CAS 188967-75-1)
- 4-(2-chloro-4-fluorosulphonylanilino)-4-oxobut-2-enoic acid (CAS 680213-38-1)
Recommended Standards
- Norflurazon-13C,d3 (CAS 1346603-47-1)
- 2-(4-Chlorophenyl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 187998-87-4)
- Urapidil impurity 100 (CAS CATO-C4X-1924100)
- 6-Chloro-1-(3,5-difluorophenyl)-1H-indole-3-carboxylic acid (CAS 921195-18-8)
- 2-(Trifluoromethyl)benzhydrol 727-98-0 phenyl(2-(trifluoromethyl)phenyl)methanol (CAS 727-98-0)
- 2-Isocyanato-2-methylpropanoic acid methyl ester (CAS 54213-21-7)
- 4-Chloro-8-methyl-2-phenylquinazoline (CAS 29209-81-2)
- 5-Fluoro-2-hydrazinylpyrimidin-4(3H)-one (CAS 1417349-42-8)
- 4-Nitro methanesulfonanilide (CAS 5825-62-7)
- 8-Aminoquinoxaline-5-carbonitrile (CAS 573758-47-1)
- (2-Phenyl-6-(pyridin-2-yl)pyrimidin-4-yl)methanol (CAS 922726-29-2)
- 2-((3-Chlorobenzyl)oxy)-5-methylbenzaldehyde (CAS 1272273-81-0)
- 29113-33-5 3,4-Dihydro-2-(ethoxycarbonyl)-4-oxoquinazoline Ethyl 1,4-dihydro-4-oxoquinazoline-2-carboxylate ethyl 4-oxo-3H-quinazoline-2-carboxylate (CAS 29113-33-5)
- Insulin Detemir (CAS 169148-63-4)
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