Nicorandil Impurity 19 CAS CATO-C4X-190719
| CAS No. | CATO-C4X-190719 |
| Molecular Formula | C8H8N2O5 |
| Molecular Weight | 212.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nicorandil Impurity 19.
As a process- or degradation-related impurity, Nicorandil Impurity 19 (CAS CATO-C4X-190719, C8H8N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Nicorandil Impurity 19 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O5 |
| Molecular Weight | 212.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Nicorandil Standards
- Nicorandil (CAS 65141-46-0)
- Nicorandil EP Impurity A (CAS 65141-47-1)
- Nicorandil Impurity 30 (CAS CATO-C4X-190730)
- Nicorandil Impurity 48 (CAS CATO-C4X-190748)
- Nicorandil Impurity 52 (CAS CATO-C4X-190752)
- Nicorandil Impurity 20 (CAS 70892-82-9)
- Nicorandil Impurity 24 (CAS 149415-43-0)
- Nicorandil-d4 (CAS 1132681-23-2)
Recommended Standards
- N-Methyl-2-((5-nitrofuran-2-yl)methylene)hydrazinecarboxamide (CAS 5407-73-8)
- 2-(3-Fluoro-5-(methoxycarbonyl)phenyl)acetic acid (CAS 1000524-91-3)
- N3-C2-NHS ester (CAS 850180-76-6)
- 3-(Trifluoromethoxy)benzoic acid (CAS 1014-81-9)
- Cabazitaxel Impurity 42 (CAS CATO-C4X-111542)
- Dotinurad Impurity 97 (CAS 1403247-12-0)
- Apixaban Impurity 113 (CAS 617-84-5)
- 5,6-Dichloro-N-(2,4-dimethoxybenzyl)-N-(thiazol-2-yl)pyridine-3-sulfonamide (CAS 2448158-12-9)
- 1-(4-Chlorobenzyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (CAS 478080-25-0)
- Valsartan Impurity 130 HCl (CAS CATO-C4X-1057130)
- 4-(Benzyloxy)butylboronic acid (CAS 2377610-35-8)
- Diethyl 2-((5-(2,3-dichlorophenyl)furan-2-yl)methylene)malonate (CAS 304896-39-7)
- (2R)-2-amino-5,5,5-trifluoro-Pentanamide (CAS 1146852-37-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com