4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine CAS 189575-70-0
| CAS No. | 189575-70-0 |
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine (CAS 189575-70-0) is a high-purity analytical reference standard with the molecular formula C13H10F3N and a molecular weight of 237.22 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 237.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-((1-Ethyl-3-(trifluoromethyl)-1h-pyrazol-5-yl)methoxy)ethan-1-amine (CAS 1170513-11-7)
- 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-amine (CAS 1214341-39-5)
- 4-(2-Methyl-3-(trifluoromethyl)phenyl)pyridine (CAS 1214378-20-7)
- 2-Methyl-4-(4-(trifluoromethyl)phenyl)pyridine (CAS 1261635-94-2)
- 2-methyl-6-[3-(trifluoromethyl)phenyl]pyridine (CAS 1261758-54-6)
- 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one (CAS 1909308-87-7)
- 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine (CAS 438-84-6)
- 2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-amine (CAS 400744-68-5)
Recommended Standards
- 4-Oxo-7-phenyl-1,4-dihydropyrazolo[5,1-c][1,2,4]triazine-3-carbonitrile (CAS 1708079-61-1)
- N-Phenyl-2-(trifluoromethyl)aniline (CAS 14925-11-2)
- 3-(Butylamino)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5(4H)-one (CAS 195511-48-9)
- 1-((3-Isopropyl-1,2,4-oxadiazol-5-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1456379-00-2)
- 6-benzyloxy-1H-indole-3-sulfonic acid (CAS 2361020-89-3)
- trans-1-Benzyl-4-(p-tolyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1956309-30-0)
- N-(4-Isopropylphenyl)benzo[d][1,2,3]thiadiazole-5-carboxamide (CAS 891025-42-6)
- 2-Methyl-2-[(2-methylbenzyl)amino]-1-propanol hydrochloride (CAS 1049773-02-5)
- (2s,3r)-2,3-Diaminobutanoic acid dihydrochloride (CAS 215652-51-0)
- Topiramate Impurity 41 (CAS CATO-C4X-176841)
- 3-(2,5-Dihydroxy-1H-pyrrol-3-yl)propane-1-sulfonic acid (CAS 754169-88-5)
- (5-Bromo-2-isopropoxyphenyl)methanol (CAS 562840-58-8)
- Diethyl acetylmalonate (CAS 570-08-1)
- Peptide 433 (CAS CATO-CPTD788433)
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