2-(Trifluoromethyl)[1,1-biphenyl]-2-amine CAS 438-84-6
| CAS No. | 438-84-6 |
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine.
CATO supplies 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine (CAS 438-84-6), a certified reference material (molecular formula C13H10F3N, MW 237.22 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine (C13H10F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-((1-Ethyl-3-(trifluoromethyl)-1h-pyrazol-5-yl)methoxy)ethan-1-amine (CAS 1170513-11-7)
- 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-amine (CAS 1214341-39-5)
- 4-(2-Methyl-3-(trifluoromethyl)phenyl)pyridine (CAS 1214378-20-7)
- 2-Methyl-4-(4-(trifluoromethyl)phenyl)pyridine (CAS 1261635-94-2)
- 2-methyl-6-[3-(trifluoromethyl)phenyl]pyridine (CAS 1261758-54-6)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine (CAS 189575-70-0)
- 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one (CAS 1909308-87-7)
- 2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-amine (CAS 400744-68-5)
Recommended Standards
- 2-((9-Ethyl-6-oxo-6,9-dihydro-3H-purin-2-yl)amino)acetic acid (CAS 749917-36-0)
- 2-((6-Oxo-6,9-dihydro-1H-purin-2-yl)amino)butanoic acid (CAS 915723-18-1)
- 2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine (CAS 209917-92-0)
- 2-((1,2,2-Tricyanovinyl)amino)benzamide (CAS 959583-36-9)
- 1-(2-Isocyanatoethyl)-1H-pyrazole (CAS 1340558-74-8)
- tert-Butyl N-(3-hydroxycyclobutyl)-n-methylcarbamate (CAS 1392804-89-5)
- N-(2-(1-Acetyl-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923202-02-2)
- Cyclopentanone (CAS 120-92-3)
- 2-Ethyl-3-methoxybenzonitrile (CAS 102236-67-9)
- Fesoterodine Impurity 26 (CAS CATO-C4X-164426)
- Stearyldiethanolamine (CAS 10213-78-2)
- 5-Methyl-4-phenylthiazol-2-amine hydrobromide (CAS 34176-31-3)
- Turmerone (CAS 82508-15-4)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com