5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one CAS 1909308-87-7
| CAS No. | 1909308-87-7 |
| Molecular Formula | C10H14F3NO2 |
| Molecular Weight | 237.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 237.22 g/mol gives 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one (CAS 1909308-87-7), molecular formula C10H14F3NO2 and molecular weight 237.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one (C10H14F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14F3NO2 |
| Molecular Weight | 237.22 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- 6-Chloro-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(methylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 866135-01-5)
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