Methyl 2-(hydroxymethyl)-1H-indole-5-carboxylate CAS 190071-26-2
| CAS No. | 190071-26-2 |
| Molecular Formula | C11H11NO3 |
| Molecular Weight | 205.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-(hydroxymethyl)-1H-indole-5-carboxylate (CAS 190071-26-2) is a high-purity analytical reference standard with the molecular formula C11H11NO3 and a molecular weight of 205.21 g/mol.
Methyl 2-(hydroxymethyl)-1H-indole-5-carboxylate (C11H11NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11NO3 |
| Molecular Weight | 205.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- 6-(Dimethylamino)phthalazine-1,4-diol (CAS 18697-31-9)
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- methyl 1,6-dimethylpyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1855889-86-9)
- methyl 5-(4-hydroxybut-1-yn-1-yl)pyridine-2-carboxylate (CAS 1909318-62-2)
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- tert-Butyl N-(4-bromo-3-fluorophenyl)-N-methylcarbamate (CAS 1881330-84-2)
- 5-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 628306-54-7)
- Methyl 3-amino-4-chlorothiophene-2-carboxylate (CAS 632356-41-3)
- 3-Chloro-2,4-diiodopyridine (CAS 1188435-00-8)
- 6-Hydroxyluteolin 7-glucoside (CAS 54300-65-1)
- Pethidine Impurity 7 (CAS 84176-78-3)
- Imidazo[2,1-b]thiazole-6-carboxylic Acid (CAS 53572-98-8)
- Flurbiprofen Impurity 98 (CAS CATO-C4X-144498)
- Nonapeptide-1 (CAS 158563-45-2)
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