Ezetimibe Impurity 40 CAS 190448-57-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.190448-57-8
Molecular FormulaC30H29F2NO9
Molecular Weight585.55 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ezetimibe Impurity 40 CAS 190448-57-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 585.55 g/mol gives Ezetimibe Impurity 40 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ezetimibe Impurity 40 (CAS 190448-57-8) is a certified pharmaceutical impurity reference standard with the molecular formula C30H29F2NO9 and a molecular weight of 585.55 g/mol.

Based on its molecular formula C30H29F2NO9, Ezetimibe Impurity 40 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 585.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC30H29F2NO9
Molecular Weight585.55 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2011
Halogen ContentF-containing
Nitrogen Atoms1

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