4-chloro-6-fluoro-8-iodoquinazoline CAS 1909319-90-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1909319-90-9
Molecular FormulaC8H3ClFIN2
Molecular Weight308.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-chloro-6-fluoro-8-iodoquinazoline CAS 1909319-90-9 chemical structure

Description

The occurrence of 4-chloro-6-fluoro-8-iodoquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-chloro-6-fluoro-8-iodoquinazoline (CAS 1909319-90-9) is a high-purity analytical reference standard with the molecular formula C8H3ClFIN2 and a molecular weight of 308.48 g/mol.

Structurally, 4-chloro-6-fluoro-8-iodoquinazoline (C8H3ClFIN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 308.48 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-chloro-6-fluoro-8-iodoquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3ClFIN2
Molecular Weight308.48 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl/I-containing
Nitrogen Atoms2

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