Dabigatran impurity 134 CAS 1912458-32-2
| CAS No. | 1912458-32-2 |
| Molecular Formula | C24H29N5O4 |
| Molecular Weight | 451.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 451.52 g/mol gives Dabigatran impurity 134 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dabigatran impurity 134 (CAS 1912458-32-2, C24H29N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H29N5O4, Dabigatran impurity 134 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 451.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dabigatran impurity 134 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29N5O4 |
| Molecular Weight | 451.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 5 |
Related Dabigatran Standards
- Dabigatran Impurity 109 (CAS CATO-C4X-1089109)
- Dabigatran Impurity 153 (CAS CATO-C4X-1089153)
- Dabigatran Impurity 43 (CAS 212322-77-5)
- Dabigatran Impurity 44 (CAS 211916-39-1)
- Dabigatran Impurity 54 (CAS 1643377-48-3)
- Dabigatran (CAS 211914-51-1)
- Dabigatran Impurity 70 (CAS CATO-C4X-108970)
- Dabigatran-d3 (CAS 1246817-44-6)
Recommended Standards
- Eltrombopag-d9 (CAS CATO-C4X-119818)
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- 17β-Estradiol-d3 3-β-D-Glucuronide (CAS 1260231-06-8)
- Valsartan Impurity 4 (Mixture of Diastereomers) (CAS 188259-69-0)
- Fexofenadine Impurity 10 (CAS CATO-C4X-179410)
- Mitoxantrone Impurity 17 (CAS CATO-C4X-103417)
- Ritonavir Impurity 52 (CAS CATO-C4X-175152)
- Venamide (CAS 19625-79-7)
- 9-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(4-methoxyphenyl)-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one (CAS 946385-19-9)
- 3-(2-Chloro-4-(2-methoxy-2-oxoethyl)phenyl)-5-methylisoxazole-4-carboxylic acid (CAS 870194-63-1)
- 3-Amino-4-ethoxy-N,N-dimethylbenzene-1-sulfonamide (CAS 22121-73-9)
- 1-(3-Bromopropyl)-3-chlorobenzene (CAS 91085-89-1)
- Azilsartan Impurity 5 (CAS 147404-76-0)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
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