Valsartan Impurity 4 (Mixture of Diastereomers) CAS 188259-69-0
| CAS No. | 188259-69-0 |
| Molecular Formula | C24H29N5O4 |
| Molecular Weight | 451.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Valsartan Impurity 4 (Mixture of Diastereomers) (CAS 188259-69-0), a pharmacopoeial impurity reference standard (molecular formula C24H29N5O4, MW 451.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C24H29N5O4, Valsartan Impurity 4 (Mixture of Diastereomers) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 451.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H29N5O4 |
| Molecular Weight | 451.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan N-Oxide 2 (CAS CATO-C4X-1057148)
- Valsartan Impurity 149 (CAS CATO-C4X-1057149)
- Valsartan N-Oxide (CAS CATO-C4X-105779)
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- Valsartan USP Related Compound E (CAS 137863-17-3)
Recommended Standards
- Dabigatran Impurity 109 (CAS CATO-C4X-1089109)
- cis-Piflutixol (CAS 60756-96-9)
- Dabigatran impurity 134 (CAS 1912458-32-2)
- AZ 628 (CAS 878739-06-1)
- Phenylalanine impurity 1 (CAS 90988-28-6)
- Mesalazine Impurity 24 (CAS 859964-08-2)
- Picosulfate Impurity 35 (CAS CATO-C4X-123735)
- 1-Ethyl-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate (CAS 174899-72-0)
- Pyrazolo[1,5-a]pyridine-3,5-dicarboxylic acid (CAS 1352892-43-3)
- 5'-Bromo-3,4'-dihexyl-2,2'-bithiophene (CAS 154717-21-2)
- 2-(3,4-Dimethylphenyl)-8-methylimidazo[1,2-a]pyridine (CAS 881041-49-2)
- 6-Bromo-3-methylbenzo[d]isoxazole, 97% (CAS 66033-69-0)
- 1-(4,5-Diethoxy-2-nitrophenyl)ethanone (CAS 1351383-11-3)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com