2-(Chloromethyl)-5-Fluorobenzoyl Chloride CAS 191934-72-2
| CAS No. | 191934-72-2 |
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-5-Fluorobenzoyl Chloride.
2-(Chloromethyl)-5-Fluorobenzoyl Chloride (CAS 191934-72-2), molecular formula C8H5Cl2FO and molecular weight 207.03 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Chloromethyl)-5-Fluorobenzoyl Chloride (C8H5Cl2FO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Chloromethyl)-5-Fluorobenzoyl Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-4-Fluorobenzoyl Chloride (CAS 191934-71-1)
- 4-(Chloromethyl)-3-Fluorobenzoyl Chloride (CAS 200418-17-3)
- 1-(Chloromethyl)-3-(p-tolyl)bicyclo[1.1.1]Pentane (CAS 2287316-98-5)
- Chloromethyl nonanoate (CAS 77877-95-3)
- 2-(chloromethyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 1039847-82-9)
- 5-(chloromethyl)-3-[1-(ethylsulfanyl)ethyl]-1,2,4-oxadiazole (CAS 1421602-63-2)
- 3-(Chloromethyl)-1-(4-methylphenyl)-1h-pyrazole (CAS 1482710-08-6)
- [5-(chloromethyl)-1-methyl-pyrazol-3-yl]methyl acetate (CAS 2489244-22-4)
Recommended Standards
- (1-Acetamido-2-phenylethyl)boronic acid (CAS 88765-81-5)
- 4-Morpholinophenylboronic acid (CAS 186498-02-2)
- (2-(Cyclopentyloxy)pyridin-4-yl)boronic acid (CAS 2225177-11-5)
- 3,4-Dichloro-2-fluoroacetophenone (CAS 1806354-87-9)
- 4-Oxo-1,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 439693-47-7)
- 4-(Bromomethyl)-2,1,3-benzothiadiazole (CAS 16405-99-5)
- tert-Butyl 3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (CAS 1174068-78-0)
- 1-[4-(Morpholine-4-carbonyl)phenyl]pyrrolidin-2-one (CAS 478039-69-9)
- 1-(1-Ethyl-1h-pyrazol-4-yl)ethane-1-thiol (CAS 1247836-33-4)
- (2-Nitrobenzoyl)glycine (CAS 10167-23-4)
- 1-Boc-3-Bromo-7-nitroindole (CAS 914349-37-4)
- 2-(Isopentylamino)-5-nitrobenzonitrile (CAS 945299-76-3)
- 1H-Imidazole-2-sulfonyl chloride hydrochloride (CAS 877861-76-2)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
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