3,4-Dichloro-2-fluoroacetophenone CAS 1806354-87-9
| CAS No. | 1806354-87-9 |
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3,4-Dichloro-2-fluoroacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3,4-Dichloro-2-fluoroacetophenone (CAS 1806354-87-9) is a high-purity analytical reference standard with the molecular formula C8H5Cl2FO and a molecular weight of 207.03 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3,4-Dichloro-2-fluoroacetophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 2-(2,4-Dichloro-5-fluorophenyl)oxirane (CAS 1179042-36-4)
- 2,2-Dichloro-1-(3-Fluorophenyl)Ethanone (CAS 127728-55-6)
- 1-(4,5-Dichloro-2-fluorophenyl)ethan-1-one (CAS 1286734-89-1)
- 2,4-Dichloro-6-cyclopropyl-5-fluoropyrimidine (CAS 1416438-39-5)
- 2,3-Dichloro-5-fluoroacetophenone (CAS 1803718-44-6)
- 2,6-Dichloro-4-fluoroacetophenone (CAS 1804886-00-7)
- 3,4-Dichloro-5-fluoroacetophenone (CAS 1806298-58-7)
- 1-(2,3-Dichloro-6-fluorophenyl)ethan-1-one (CAS 870704-16-8)
Recommended Standards
- 4-Morpholinophenylboronic acid (CAS 186498-02-2)
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- 2-Chloro-6-fluorophenylacetyl chloride (CAS 179314-61-5)
- 4-Hydroxy-6,7-dichloroquinoline (CAS 203626-51-1)
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- 5,6-dihydroxy-1-benzothiophene-2-carboxylic acid (CAS 97852-77-2)
- 1-(4-Isopropylpyrimidin-2-yl)ethan-1-amine (CAS 1343627-54-2)
- (E)-3-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)-[1,1'-biphenyl]-2-carbonitrile (CAS 2171558-36-2)
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