Darunavir Impurity 27 CAS 192725-55-6
| CAS No. | 192725-55-6 |
| Molecular Formula | C13H13NO7 |
| Molecular Weight | 295.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Darunavir Impurity 27.
CATO supplies Darunavir Impurity 27 (CAS 192725-55-6), a pharmacopoeial impurity reference standard (molecular formula C13H13NO7, MW 295.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Darunavir Impurity 27 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 295.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Darunavir Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13NO7 |
| Molecular Weight | 295.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Nitrogen Atoms | 1 |
Related Darunavir Standards
- Darunavir Impurity 40 (CAS 143225-31-4)
- Darunavir Impurity 41 (CAS 388073-93-6)
- Darunavir Impurity 29 (CAS 98-74-8)
- Darunavir impurity 14, 98% (CAS 143224-62-8)
- Darunavir Impurity 14 (CAS CATO-C4X-160614)
- Darunavir Impurity 15 (CAS 192800-79-6)
- Darunavir Impurity 16 (CAS 1402142-62-4)
- Darunavir Intermediate 22 (CAS 169280-56-2)
Recommended Standards
- Levofloxacin Impurity 96 (CAS CATO-C4X-137196)
- Ofloxacin Impurity 8 (CAS CATO-C4X-17178)
- Moxifloxacin Impurity 12 (CAS 112811-72-0)
- Sparfloxacin Impurity 4 (CAS CATO-C4X-21134)
- Tryptophan Impurity 49 (CAS CATO-C4X-137349)
- Sucralfate EP Impurity A Octasodium Salt (CAS 74135-10-7)
- Bosutinib Impurity N3 (CAS 17722-32-6)
- Clofarabine Impurity 6 (CAS 97614-43-2)
- 4-(3-Aminophenyl)-N,N-dimethylthiazol-2-amine (CAS 1281363-96-9)
- tert-Butyl 7-(difluoromethyl)-2,6-diazaspiro[3.4]octane-2-carboxylate (CAS 2768872-82-6)
- (2-Cyclopropyl-4-(1H-pyrazol-1-yl)phenyl)boronic acid (CAS 2225178-85-6)
- 4-((4-Formylphenyl)(methyl)amino)benzonitrile (CAS 1282235-93-1)
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 578001-34-0)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
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