Darunavir Impurity 29 CAS 98-74-8
| CAS No. | 98-74-8 |
| Molecular Formula | C6H4ClNO4S |
| Molecular Weight | 221.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Darunavir Impurity 29 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Darunavir Impurity 29 (CAS 98-74-8), a pharmacopoeial impurity reference standard (molecular formula C6H4ClNO4S, MW 221.62 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Darunavir Impurity 29 (C6H4ClNO4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H4ClNO4S |
| Molecular Weight | 221.62 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Darunavir Standards
- Darunavir Impurity 17 (CAS 866594-61-8)
- Darunavir Impurity 18 (CAS 1932330-83-0)
- Darunavir Impurity 19 (CAS 1932353-11-1)
- Darunavir Impurity 21 (CAS 866594-60-7)
- Darunavir Impurity 27 (CAS 192725-55-6)
- Darunavir Impurity 47 (CAS 156928-09-5)
- Darunavir Impurity 24 (CAS 252873-00-0)
- Darunavir Impurity 40 (CAS 143225-31-4)
Recommended Standards
- 4-Chloro-8-fluoro-5H-pyrimido[5,4-b]indole (CAS 331443-96-0)
- 2-Nitrobenzenesulfonyl Chloride (CAS 1694-92-4)
- 4-Chloro-7-fluoroimidazo[1,2-a]quinoxaline (CAS 251649-58-8)
- 1-(5-Chloro-2-(difluoromethoxy)phenyl)ethan-1-amine (CAS 1249652-75-2)
- Epinephrine /Adrenaline Impurity 56 (CAS 25015-92-3)
- Lumateperone Impurity 56 (CAS CATO-C4X-220156)
- Evocalcet Impurity 14 (CAS 870964-68-4)
- Mirabegron N-Glucuronide (CAS 1365244-65-0)
- Bilastine impurity 88 (CAS 1316734-06-1)
- 2-methylbutane-1-sulfonyl fluoride (CAS 1311315-63-5)
- N-(2,3-Dimethylphenyl)glycine (CAS 83442-59-5)
- 4-(Difluoromethyl)-3-fluoro-5-methoxypicolinic acid (CAS 1805440-78-1)
- 3-(4-Biphenylyl)-2-cyanopropionic Acid (CAS 2044707-23-3)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com