4-Bromo-3-iodo-5-nitropyridin-2-amine CAS 1934875-43-0
| CAS No. | 1934875-43-0 |
| Molecular Formula | C5H3BrIN3O2 |
| Molecular Weight | 343.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Bromo-3-iodo-5-nitropyridin-2-amine (CAS 1934875-43-0), molecular formula C5H3BrIN3O2 and molecular weight 343.90 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-3-iodo-5-nitropyridin-2-amine (C5H3BrIN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Bromo-3-iodo-5-nitropyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3BrIN3O2 |
| Molecular Weight | 343.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 6-Bromo-5-iodo-3-nitropyridin-2-amine (CAS 1936348-78-5)
- 2-Bromo-4-iodo-6-nitrophenol (CAS 1936643-46-7)
- 4-Bromo-2-iodo-6-nitrophenol (CAS 58349-02-3)
- 6-Bromo-3-iodo-2-nitrophenol (CAS 2090513-56-5)
- 3-Bromo-2-fluoro-6-iodobenzamide (CAS 217816-60-9)
- 2-Bromo-6-iodo-3,4-dimethoxypyridine (CAS 1305324-63-3)
- 2-Bromo-5-iodo-3-methoxy-1-methylpyridin-4(1H)-one (CAS 1346446-83-0)
- 5-Bromo-3-iodo-2,6-dimethoxypyridine (CAS 1826110-09-1)
Recommended Standards
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 22 (CAS CATO-C4X-183722)
- Clemastine Impurity 21 (CAS CATO-C4X-183721)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- 3-(4-Methoxyphenyl)-N-(4-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-01-7)
- 5-(2-(Trifluoromethyl)phenyl)isoxazol-3-amine (CAS 1498502-41-2)
- 5-(Chloromethyl)-3-(propan-2-yl)-4,5-dihydro-1,2-oxazole (CAS 1311318-05-4)
- Baricitinib Impurity N5 (CAS 1153949-15-5)
- 2-(2,3-Dihydroxyquinoxalin-6-yl)acetic acid (CAS 1017376-92-9)
- (2S,5S)-Methyl 5-ethylpyrrolidine-2-carboxylate (CAS 97465-31-1)
- 7-Chloro-4-(chloromethyl)-2H-chromen-2-one (CAS 273747-43-6)
- Cyclobutylmethanamine (CAS 4415-83-2)
- 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one (CAS 532394-23-3)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com