Marbofloxacin EP Impurity E CAS 2249835-04-7
| CAS No. | 2249835-04-7 |
| Molecular Formula | C18H23FN4O4 |
| Molecular Weight | 378.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Marbofloxacin EP Impurity E (CAS 2249835-04-7, C18H23FN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Marbofloxacin EP Impurity E (C18H23FN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 378.40 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23FN4O4 |
| Molecular Weight | 378.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Marbofloxacin Standards
- Marbofloxacin EP Impurity F (CAS 194023-72-8)
- Marbofloxacin Impurity 10 (CAS CATO-C4X-180010)
- Marbofloxacin-d8 (CAS 1185053-37-5)
- Marbofloxacin (CAS 115550-35-1)
- Marbofloxacin EP Impurity C (CAS 100276-37-7)
- Marbofloxacin EP Impurity D (CAS 117380-92-4)
- Marbofloxacin EP Impurity B (CAS 115551-41-2)
- Marbofloxacin Impurity 9 (CAS 100276-67-3)
Recommended Standards
- 5-HO-EHDPP (CAS 2173149-33-0)
- Iguratimod Impurity 11 (CAS 149456-98-4)
- Ampicillin Impurity 94 (CAS CATO-C4X-144394)
- Iguratimod Impurity 27 (CAS CATO-C4X-182627)
- Zopiclone EP Impurity B (CAS 43200-81-3)
- Lurasidone Impurity 43 2HCl (CAS 1260025-93-1)
- Gatifloxacin Impurity 23 (CAS 112811-58-2)
- Dimethyl 3-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)cyclopent-3-ene-1,1-dicarboxylate (CAS 159429-83-1)
- Pregabalin Impurity 27 (CAS 172796-26-8)
- 3-Bromo-5-(chloromethyl)benzonitrile (CAS 1261775-65-8)
- 5-chloro-8-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride (CAS 1251925-38-8)
- (2-Bromo-4-methylphenyl)hydrazine (CAS 67156-57-4)
- methyl 4-chloro-2-fluoro-6-methoxybenzoate (CAS 1823338-45-9)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
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