6-(Difluoromethyl)pyridin-2(1H)-one CAS 195044-11-2
| CAS No. | 195044-11-2 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-(Difluoromethyl)pyridin-2(1H)-one (C6H5F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 145.11 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 6-(Difluoromethyl)pyridin-2(1H)-one (CAS 195044-11-2), a certified reference material (molecular formula C6H5F2NO, MW 145.11 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 5-(Difluoromethyl)pyridin-3-ol (CAS 1393541-20-2)
- 5-(Difluoromethyl)-2(1H)-pyridinone 1402550-75-7 5-(Difluoromethyl)pyridin-2(1H)-one (CAS 1402550-75-7)
- 1-(difluoromethyl)-1H-pyrrole-2-carbaldehyde (CAS 1519187-90-6)
- 6-(Difluoromethyl)pyrimidin-4-amine (CAS 1706464-15-4)
- 4-(Difluoromethyl)pyridin-2(1H)-one (CAS 1780500-70-0)
- 4-(Difluoromethyl)pyrimidin-2-amine (CAS 1780891-13-5)
- 2-(Difluoromethyl)pyrimidin-5-amine (CAS 1781133-28-5)
- 3-(Difluoromethyl)pyrazin-2-amine (CAS 1785423-85-9)
Recommended Standards
- (3R)-5-Oxo-3-morpholinecarboxylic acid (CAS 1932539-63-3)
- 6,6-difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile (CAS 1955557-96-6)
- (R)-3-methyl-2-oxooxazolidine-5-carboxylic acid (CAS 1894463-12-7)
- O-(3,5-difluorophenyl)hydroxylamine (CAS 197588-25-3)
- N-(3-Chlorophenyl)hydrazinecarbothioamide (CAS 42135-76-2)
- 2-(Difluoromethyl)-4,5-diiodopyridine-3-acetonitrile (CAS 1806898-05-4)
- 3-Oxours-12-en-28-oic Acid (CAS 6246-46-4)
- n-(2-Methyl-5-(methylsulfonyl)phenyl)isobutyramide (CAS 1090622-76-6)
- 2-((2-(Furan-2-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one (CAS 729570-18-7)
- tert-Butyl 3-formyl-3-methoxyazetidine-1-carboxylate (CAS 1781321-90-1)
- 2-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]oxy-N-prop-2-ynyl-acetamide (CAS 2703765-24-4)
- Ethyl 2-(6-methylpyridin-3-yl)cyclopropane-1-carboxylate (CAS 1251905-92-6)
- tert-butyl (3S)-3-iodopiperidine-1-carboxylate (CAS 1354004-63-9)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com