Cefotaxime Impurity 60 CAS 1950566-47-8
| CAS No. | 1950566-47-8 |
| Molecular Formula | C16H17ClN2O4S |
| Molecular Weight | 368.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefotaxime Impurity 60.
CATO supplies Cefotaxime Impurity 60 (CAS 1950566-47-8), a pharmacopoeial impurity reference standard (molecular formula C16H17ClN2O4S, MW 368.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Cefotaxime Impurity 60 (C16H17ClN2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefotaxime Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17ClN2O4S |
| Molecular Weight | 368.84 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Cefotaxime Standards
- Cefotaxime Impurity 69 (CAS CATO-C4X-120169)
- Cefotaxime Impurity 49 (CAS 130468-09-6)
- Cefotaxime Impurity 47 (CAS 474956-63-3)
- Cefotaxime Impurity 48 (CAS CATO-C4X-120148)
- Cefotaxime Impurity 52 (CAS 57254-16-7)
- Cefotaxime Impurity 33 (CAS CATO-C4X-120133)
- Cefotaxime Impurity 36 (CAS CATO-C4X-120136)
- Cefotaxime Impurity 37 (CAS CATO-C4X-120137)
Recommended Standards
- N-[(2E)-2-(4-Chlorophenyl)-2-(methoxyimino)ethyl]-4-methoxybenzene-1-sulfonamide (CAS 551921-51-8)
- N-(4-Chlorophenyl)-2-((5-(hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)acetamide (CAS 923139-74-6)
- Cefazolin Impurity 56 (CAS 106773-36-8)
- N-(3-Chlorophenyl)-2-((5-(hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)acetamide (CAS 923678-24-4)
- Valsartan Impurity 53 (CAS 137863-42-4)
- Ceftriaxone impurity 49 (CAS CATO-C4X-116349)
- Lufenuron EP Impurity B (CAS 2767988-84-9)
- 2-Deoxy-D-glucose-6-phosphate sodium salt, 98% (CAS 33068-19-8)
- 2-Bromo-1-(2-iodophenyl)ethan-1-one (CAS 113258-84-7)
- Varenicline Impurity 55 (CAS CATO-C4X-196255)
- Antofloxacin hydrochloride (CAS 873888-67-6)
- Diethyl 3-fluorocyclobutane-1,1-dicarboxylate (CAS 123812-76-0)
- 2,6-Difluoro-3-iodobenzonitrile (CAS 1447606-20-3)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com