Cefotaxime Impurity 52 CAS 57254-16-7
| CAS No. | 57254-16-7 |
| Molecular Formula | C15H13N3O3S3 |
| Molecular Weight | 379.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C15H13N3O3S3, Cefotaxime Impurity 52 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 379.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Cefotaxime Impurity 52 (CAS 57254-16-7) is a certified pharmaceutical impurity reference standard with the molecular formula C15H13N3O3S3 and a molecular weight of 379.48 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H13N3O3S3 |
| Molecular Weight | 379.48 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related Cefotaxime Standards
- Cefotaxime Impurity 33 (CAS CATO-C4X-120133)
- Cefotaxime Impurity 48 (CAS CATO-C4X-120148)
- Cefotaxime Impurity 49 (CAS 130468-09-6)
- Cefotaxime Impurity 60 (CAS 1950566-47-8)
- Cefotaxime Impurity 69 (CAS CATO-C4X-120169)
- Cefotaxime Impurity 47 (CAS 474956-63-3)
- Cefotaxime Impurity 22 (CAS CATO-C4X-120122)
- Cefotaxime EP Impurity A (CAS 65052-63-3)
Recommended Standards
- N-cyclopentyl-2-(4-(4-(thiophen-2-yl)pyrimidin-2-yl)phenoxy)acetamide (CAS 477888-53-2)
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- N-(6-(Methylsulfonyl)benzo[d]thiazol-2-yl)-2-(methylthio)nicotinamide (CAS 763100-63-6)
- Olopatadine Impurity N2 (CAS 1206456-44-1)
- Crisaborole impurity 155 (CAS CATO-C4X-2021155)
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- Ornidazole Impurity 43 (CAS CATO-C4X-133143)
- N-Cyclopropyl-3-oxobutanamide (CAS 110262-87-8)
- 3-Bromo-4-methylpyridine 1-oxide (CAS 17117-15-6)
- tert-butyl 4-formyl-7-methyl-5-(trideuteriomethoxy)indole-1-carboxylate (CAS 1481631-52-0)
- 5-(2,7-Dimethoxynaphthalen-1-yl)-1,3,4-oxadiazol-2-amine (CAS 1706449-00-4)
- 3-Amino-1-(2,4-dimethylphenyl)propan-1-ol (CAS 1215954-90-7)
- (2Z)-2-cyano-3-(2,5-dimethyl-1-propyl-1H-pyrrol-3-yl)prop-2-enethioamide (CAS 852217-78-8)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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