Canagliflozin Impurity 11 CAS 1951467-29-0
| CAS No. | 1951467-29-0 |
| Molecular Formula | C24H25FO6S |
| Molecular Weight | 460.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 460.52 g/mol gives Canagliflozin Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Canagliflozin Impurity 11 (CAS 1951467-29-0) is a certified pharmaceutical impurity reference standard with the molecular formula C24H25FO6S and a molecular weight of 460.52 g/mol.
Canagliflozin Impurity 11 (C24H25FO6S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Canagliflozin Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H25FO6S |
| Molecular Weight | 460.52 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin impurity 115 (CAS CATO-C4X-1123115)
- Canagliflozin impurity 118 (CAS CATO-C4X-1123118)
- Canagliflozin Impurity 14 (CAS CATO-C4X-112314)
- Canagliflozin Impurity 37 (CAS 1672658-93-3)
- Canagliflozin Impurity 43 (CAS CATO-C4X-112343)
- Canagliflozin Impurity 44 (CAS CATO-C4X-112344)
- Canagliflozin Impurity 49 (CAS CATO-C4X-112349)
- Canagliflozin Impurity 50 (CAS CATO-C4X-112350)
Recommended Standards
- Tris(4-(oxiran-2-ylmethoxy)phenyl)methane (CAS 43224-82-4)
- Tri-N-Boc-L-Norarginine (CAS 869094-29-1)
- Pseudoaspidin (CAS 478-28-4)
- Octyl 2-3-4-6-tetra-O-acetyl-β-D-glucopyranoside (CAS 38954-67-5)
- Terbutaline Impurity 59 (CAS 3378-72-1)
- Levofloxacin EP Impurity F (CAS 100986-89-8)
- Dasatinib Impurity 52 (CAS 2169776-07-0)
- cis-2-methylcyclopropanecarboxylic acid (CAS 6142-57-0)
- (dimethyl(phenyl)silyl)methanol (CAS 17881-97-9)
- 1-[(2-chloro-4-fluorophenyl)methyl]-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 926206-27-1)
- Opicapone Impurity 93 (CAS CATO-C4X-240493)
- 3-Methylphenylacetone, 99% (CAS 18826-61-4)
- 3-(3-Nitrobenzoyl)phenyl acetate (CAS 890099-77-1)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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