Canagliflozin Impurity 14 CAS CATO-C4X-112314
| CAS No. | CATO-C4X-112314 |
| Molecular Formula | C24H25FO6S |
| Molecular Weight | 460.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Canagliflozin Impurity 14.
As a process- or degradation-related impurity, Canagliflozin Impurity 14 (CAS CATO-C4X-112314, C24H25FO6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Canagliflozin Impurity 14 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H25FO6S |
| Molecular Weight | 460.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 11 (CAS 1951467-29-0)
- Canagliflozin impurity 115 (CAS CATO-C4X-1123115)
- Canagliflozin impurity 118 (CAS CATO-C4X-1123118)
- Canagliflozin Impurity 37 (CAS 1672658-93-3)
- Canagliflozin Impurity 43 (CAS CATO-C4X-112343)
- Canagliflozin Impurity 44 (CAS CATO-C4X-112344)
- Canagliflozin Impurity 49 (CAS CATO-C4X-112349)
- Canagliflozin Impurity 50 (CAS CATO-C4X-112350)
Recommended Standards
- Tris(4-(oxiran-2-ylmethoxy)phenyl)methane (CAS 43224-82-4)
- Tri-N-Boc-L-Norarginine (CAS 869094-29-1)
- Pseudoaspidin (CAS 478-28-4)
- Canagliflozin Impurity 60 (CAS CATO-C4X-112360)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
- Tofacitinib Impurity 97 (CAS CATO-C4X-107997)
- Methylene blue Impurity 6 (CAS 4727-46-2)
- 1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 144634-02-6)
- Dapoxetine Impurity 13 (CAS 94305-25-6)
- 2-[2-(4-ethoxyphenyl)-1,3-thiazol-4-yl]acetic acid (CAS 927973-30-6)
- 722-56-5 A837466 bis(oxidanyl)-oxidanylidene-azanium; diphenyliodanium dihydroxy(oxo)ammonium; diphenyliodonium (CAS 722-56-5)
- 1-(4-Methoxyphenyl)-3-methyl-2-piperazinone (CAS 1094603-13-0)
- (2,6-Dimethylphenyl)methanamine; hydrochloride (CAS 345665-28-3)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
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