Levofloxacin EP Impurity F CAS 100986-89-8
| CAS No. | 100986-89-8 |
| Molecular Formula | C13H9F2NO4 |
| Molecular Weight | 281.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Levofloxacin EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Levofloxacin EP Impurity F (CAS 100986-89-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9F2NO4 and a molecular weight of 281.21 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Levofloxacin EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9F2NO4 |
| Molecular Weight | 281.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Levofloxacin Standards
- Levofloxacin Impurity 16 (CAS 82419-35-0)
- Levofloxacin Impurity 20 (CAS 2206360-62-3)
- Levofloxacin impurity 72 (CAS CATO-C4X-137172)
- Levofloxacin Impurity 51 (CAS 1026952-91-9)
- Levofloxacin Impurity 12 (CAS 1798887-79-2)
- Levofloxacin impurity 91 (CAS 151250-74-7)
- Levofloxacin Impurity 18 (CAS 431058-46-7)
- Levofloxacin impurity 90 (CAS CATO-C4X-137190)
Recommended Standards
- Moxifloxacin Impurity 23 (CAS 154093-72-8)
- Ofloxacin EP Impurity A (CAS 110548-07-7)
- N-(3,4-difluorophenyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861208-53-9)
- Methyl 5-formyl-3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate (CAS 946605-34-1)
- Beclometasone Impurity 44 (CAS 18769-20-5)
- Abemaciclib Impurity 68 (CAS 2138499-06-4)
- Chlorpromazine Impurity 8 (CAS 58-40-2)
- 5-Bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1190321-63-1)
- 4-(4-Chlorophenoxy)-3-fluorobenzonitrile (CAS 1153105-44-2)
- 3-Ethynyl-5-methoxypicolinic acid (CAS 2767259-24-3)
- trans-1,2-Dithiane-4,5-diol (CAS 14193-38-5)
- (2E)-3-(2-Chlorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 107943-21-5)
- 5-Bromo-3-(2-chlorophenyl)-1H-indazole (CAS 163434-09-1)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com