Lomefloxacin Impurity 7 CAS 195259-19-9
| CAS No. | 195259-19-9 |
| Molecular Formula | C15H18FN3O3 |
| Molecular Weight | 307.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lomefloxacin Impurity 7.
As a process- or degradation-related impurity, Lomefloxacin Impurity 7 (CAS 195259-19-9, C15H18FN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lomefloxacin Impurity 7 (C15H18FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H18FN3O3 |
| Molecular Weight | 307.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Lomefloxacin Standards
- Lomefloxacin Impurity 9 (CAS 183235-15-6)
- Lomefloxacin Impurity 11 (CAS CATO-C4X-207311)
- Lomefloxacin Impurity N1 (CAS 195259-11-1)
- Lomefloxacin Impurity 8 (CAS 195259-12-2)
- Lomefloxacin Impurity 19 (CAS CATO-C4X-207319)
- Lomefloxacin Impurity 2 (CAS 99726-76-8)
- Lomefloxacin Impurity 1 (CAS 75338-42-0)
- Lomefloxacin Impurity 18 (CAS CATO-C4X-207318)
Recommended Standards
- Avibactam Impurity 41 (CAS CATO-C4X-134841)
- Glutathione Reduced (CAS 70-18-8)
- Pitavastatin Impurity 85 (CAS CATO-C4X-103785)
- Diphenyl((phenylamino)methyl)phosphine oxide (CAS 111862-90-9)
- Lornoxicam impurity 60 (CAS 123252-96-0)
- Atorvastatin Impurity 52 (CAS 42558-54-3)
- Fesoterodine Impurity 16 (CAS 161497-18-3)
- Iohexol Impurity 48 (CAS 2992672-98-5)
- Methyl 1-chloroisoquinoline-6-carboxylate (CAS 1357946-43-0)
- 3-(Trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline (CAS 866040-94-0)
- 1-(1-(Bromomethyl)cyclopropyl)-4-methoxybenzene (CAS 958027-81-1)
- β-hederin (CAS 35790-95-5)
- 3-(6-Methoxypyridin-2-yl)propan-1-amine (CAS 944903-39-3)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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