Ramelteon Impurity N39 CAS 196597-69-0
| CAS No. | 196597-69-0 |
| Molecular Formula | C11H9BrO2 |
| Molecular Weight | 253.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ramelteon Impurity N39 (C11H9BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ramelteon Impurity N39 (CAS 196597-69-0) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9BrO2 and a molecular weight of 253.09 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ramelteon Impurity N39 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9BrO2 |
| Molecular Weight | 253.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | Br-containing |
Related Ramelteon Standards
- Ramelteon Impurity N40 (CAS 1221160-70-8)
- Ramelteon Impurity 23 (CAS 196597-30-5)
- Ramelteon Impurity 30 (CAS CATO-C4X-262230)
- Ramelteon impurity 46 (CAS 1365920-11-1)
- Ramelteon Impurity 5 (CAS 880152-62-5)
- Ramelteon Impurity 63 (CAS CATO-C4X-262263)
- Ramelteon Impurity 64 (CAS 1252018-55-5)
- Ramelteon Impurity 65 (CAS 2819252-94-1)
Recommended Standards
- 1-(6-Amino-5-bromo-1H-indol-1-yl)ethan-1-one (CAS 1000343-17-8)
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- 1-(5-Amino-7-bromo-1H-indol-1-yl)ethanone (CAS 1000343-32-7)
- 2-bromo-2-methylpropanedioic acid diethyl ester 29263-94-3 A819852 diethyl 2-bromanyl-2-methyl-propanedioate (CAS 29263-94-3)
- Lufenuron EP Impurity H (CAS CATO-C4X-28877)
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- 2-Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol (CAS 1314922-47-8)
- N-(4-amino-2-chlorophenyl)-2,2,2-trifluoroacetamide (CAS 766519-21-5)
- Tert-butyl 7-bromo-2-(trimethylsilyl)-1H-indole-1-carboxylate (CAS 1359828-88-8)
- 2,4-Dichloro-6-methyl-5,6,7,8-tetrahydroquinazoline (CAS 1465063-86-8)
- Ivacaftor Impurity 3 (CAS 873055-57-3)
- 4-Benzyl-2-methyloxazolidin-5-one (CAS 113825-47-1)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com