3,3'-Bis(methylthio)-[1,1'-biphenyl]-4,4'-diol CAS 197148-67-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,3'-Bis(methylthio)-[1,1'-biphenyl]-4,4'-diol.

CATO supplies 3,3'-Bis(methylthio)-[1,1'-biphenyl]-4,4'-diol (CAS 197148-67-7), a certified reference material (molecular formula C14H14O2S2, MW 278.39 g/mol) for analytical method development and quality control.

The molecular framework of 3,3'-Bis(methylthio)-[1,1'-biphenyl]-4,4'-diol (C14H14O2S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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